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Specific changes of enteric mycobiota and virome in inflammatory bowel disease
Author(s) -
Chu Yi,
Jiang Ming Zuo,
Xu Bing,
Wang Wei Jie,
Chen Di,
Li Xiao Wei,
Zhang Yu Jie,
Liang Jie
Publication year - 2018
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/1751-2980.12570
Subject(s) - human virome , mycobiota , inflammatory bowel disease , dysbiosis , medicine , disease , microbiome , immunology , population , pathogenesis , gut flora , biology , bioinformatics , metagenomics , environmental health , pathology , genetics , ecology , gene
One of the important features of inflammatory bowel disease (IBD) is dysbiosis of the gut microbiota. It has been well documented that changes in the commensal bacterial population are involved in IBD development. However, the function of the fungal and viral communities in IBD remains unclear. Moreover, the optimal treatment for IBD patients with opportunistic infections is still undecided. This review focused on how the enteric mycobiota and virome changes during the pathogenesis of IBD and discussed potential treatment strategies that open new insights into the managements of IBD.