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Fast‐track surgery combined with laparoscopy could improve postoperative recovery of low‐risk rectal cancer patients: A randomized controlled clinical trial
Author(s) -
Feng Fan,
Li Xiao Hua,
Shi Hai,
Wu Guo Sheng,
Zhang Hong Wei,
Liu Xiao Nan,
Zhao Qing Chuan
Publication year - 2014
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/1751-2980.12142
Subject(s) - medicine , perioperative , laparoscopy , colorectal cancer , fast track , randomized controlled trial , surgery , defecation , cancer
Objective In this study we aimed to assess the feasibility and safety of fast‐track surgery ( FTS ) combined with laparoscopy for treating patients with rectal cancer and compare the results with those of the conventional perioperative intervention group. Methods A total of 120 patients with rectal cancer were prospectively randomly assigned to the FTS combined with laparoscopy group and the conventional perioperative intervention plus laparoscopy group from N ovember 2011 to N ovember 2012. All patients received radical anterior resection with total mesorectal excision. Their baseline characteristics and the perioperative outcomes were recorded for analyses. Results Compared with the conventional perioperative intervention group, the fast‐track protocol combined with laparoscopy could shorten the time to the first flatus (53.44 ± 23.64 h vs 67.85 ± 20.12 h, P = 0.001) and first defecation (65.23 ± 22.24 h vs 86.98 ± 24.85 h, P = 0.000) after operation, accelerate the decrease of white blood cell count ( P < 0.05), inhibit body temperature augmentation ( P < 0.05) and reduce postoperative complication rate (16.9% vs 3.5%, P = 0.030). In addition, the length of postoperative stay was also shortened (5.05 ± 1.38 days vs 6.98 ± 2.26 days, P = 0.000). The medical cost of hospitalization was also reduced in the FTS group.Conclusion FTS in combination with laparoscopy may accelerate the clinical recovery of patients with rectal cancer after surgery.