Premium
Spontaneous abdominopelvic abscess as an initial manifestation of C rohn's disease: A retrospective cohort review
Author(s) -
Law SiuTong,
Li Kin Kong,
Wong Ho Wing
Publication year - 2013
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/1751-2980.12058
Subject(s) - medicine , abscess , pathological , retrospective cohort study , gastroenterology , crohn's disease , cohort , disease , inflammatory bowel disease , surgery
Objective The study aimed to compare the clinical characteristics of abdominopelvic (AP) abscess in patients with and without newly diagnosed Crohn's disease (CD). Methods We investigated 91 consecutive patients with AP abscess (14 newly diagnosed with CD ) from J anuary 2001 to D ecember 2010. The clinical, radiological, microbiological and pathological features and patients' outcomes were evaluated. Results Patients with newly diagnosed CD were younger (42.5 vs 57.9 years, P = 0.004), more associated with fever (50.0% vs 13.0%, P = 0.004) and weight loss (21.4% vs 3.9%, P = 0.045), and normoglycemic (5.2 mmol/L vs 6.7 mmol/L, P = 0.001). Their abscesses, located predominantly at the paracolic gutter region ( P = 0.002) were associated with fistulae ( P = 0.001) and caused by transmural bowel wall inflammation. More patients in the CD group required temporarily parenteral nutritional support ( P = 0.000) and had a longer hospital stay ( P = 0.045) and a higher local recurrent rate ( P = 0.000).Conclusion AP abscesses associated with newly diagnosed CD display distinct clinical behavior with a high risk of local recurrence.