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Protective Effect of Selenium‐Enriched Red Radish Sprouts on Carbon Tetrachloride‐Induced Liver Injury in Mice
Author(s) -
Jia Li,
Wang Tao,
Sun Yuanyuan,
Zhang Miaoran,
Tian Jiyuan,
Chen Hui,
Shen Zhenguo,
Khan Abro Hashmat,
Su Nana,
Cui Jin
Publication year - 2019
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/1750-3841.14727
Subject(s) - selenium , carbon tetrachloride , antioxidant , chemistry , raphanus , food science , functional food , liver injury , ccl4 , biochemistry , botany , biology , pharmacology , organic chemistry
This study aimed to investigate the effect of Se (Selenium) treatment on nutritional quality in radish sprouts. The results showed that 15 µM sodium selenite significantly increased phenolics compounds, flavonoids compounds, anthocyanins, and some essential amino acid content, while improving the total antioxidant capacity of radish sprouts. Besides, the Se‐enriched radish sprouts significantly alleviated the liver damage caused by carbon tetrachloride (CCl 4 ) in mice and improved the antioxidant capacity of the liver in mice, whereas the Se‐enriched radish sprouts alleviated the inflammatory reaction and apoptosis caused by CCl 4 . These results imply that Se‐enriched radish sprouts have a positive impact on mice with CCl 4 ‐induced liver injury, and that in future Se‐enriched radish sprouts could be developed into an effective food and health care product for the liver injury prevention. Practical Application Because selenium is an essential trace element in the human body, selenium‐enriched sprouts can help eliminate free radicals in the body, relieve aging, and selenium‐deficient diseases. They are easy to grow and have low costs. Hence, selenium‐enriched sprouts have a great potential of being widely consumed.