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Evaluation of the Cellular and Animal Models for the Study of Antioxidant Activity: A Review
Author(s) -
Zhang Huijuan,
Yin Meng,
Huang Lianyan,
Wang Jing,
Gong Lingxiao,
Liu Jie,
Sun Baoguo
Publication year - 2017
Publication title -
journal of food science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 150
eISSN - 1750-3841
pISSN - 0022-1147
DOI - 10.1111/1750-3841.13605
Subject(s) - antioxidant , stressor , animal model , oxidative stress , biochemical engineering , computational biology , biology , neuroscience , biochemistry , engineering , endocrinology
The mechanisms of antioxidant activities of phytochemicals are highly complex, so various methods to study them have been developed. However, the diverse available methods show inconsistent results. Different stressors, cell models, and animal models have been used to evaluate the antioxidant properties of phytochemicals. However, the literature still lacks a summary of the effects of different stressors, cell models, and animal models on the evaluation of antioxidant activities. Therefore, the mechanisms of action of different oxidative stimuli and the characteristics of the available cell models and animal models are summarized in this review.