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Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract
Author(s) -
Kwon MuGil,
Kim DeukSu,
Lee JeongHwan,
Park SeRa,
Ahn Junsik,
Kim JooSung,
Ko Kinarm,
Park Sungsu,
Kang YoungSun,
Choo YoungKug,
Ko Kisung
Publication year - 2013
Publication title -
entomological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.421
H-Index - 20
eISSN - 1748-5967
pISSN - 1738-2297
DOI - 10.1111/1748-5967.12011
Subject(s) - pupa , biology , sperm , larva , bombyx mori , reproductive system , andrology , toxicology , botany , endocrinology , biochemistry , gene , medicine
A male silkworm pupae extract with herbal mixtures such as R ubus coreanus M iquel, C hinese matrimony vine A canthopanax senticosus and tocopherol can be effectively used to recover or boost stamina. In this study, the effect of the male silkworm pupae extract on the reproductive system of S prague– D awley male rats was investigated. No clinical symptoms, and no dying or dead animals were found among experimental male silkworm larvae extract, male silkworm pupae extract and control rat groups during the study. No significant differences were found in body weights, feed or water consumption, or macroscopic examination among the three groups. No lesion was found upon necropsy. However, sperm in the group treated with male silkworm pupae extract were significantly more active than sperm in the control group. Sperm counts in both male groups treated with male silkworm larvae extract and male silkworm pupae extract were significantly higher than sperm counts in the control group. Analysis of phospholipid–hydroperoxide glutathione peroxidase ( PHGPx ) gene expression showed that the male silkworm pupae extract increased expression in testes by 26.7%. This study shows that the male silkworm pupae extract has potential to be used to enhance the function of the human reproductive system.