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Relationship Between Mortality and Cancer‐Bearing Status in Patients With Chronic Kidney Disease Who Attended an Educational Program
Author(s) -
Tanaka Akihito,
Inaguma Daijo,
Watanabe Yu,
Murata Minako,
Shinjo Hibiki,
Koike Kiyomi,
Otsuka Yasuhiro,
Takeda Asami
Publication year - 2018
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/1744-9987.12598
Subject(s) - medicine , malignancy , kidney disease , dialysis , creatinine , disease , observational study , cancer , chronic renal disease , renal replacement therapy
Patients with malignancy have a poorer prognosis than others do, which must be taken into consideration when treating them for chronic kidney disease (CKD). However, there are few studies investigating their prognosis. This was an observational study of 515 (394 men and 121 women) stable non‐dialysis patients with CKD who attended a CKD educational program. Mean age was 68.8 ± 13.0 years. Median follow‐up was 968.5 days. Mean creatinine was 3.4 ± 1.6 mg/dL. Of these, 63 had malignancy and 452 did not; 20.6% of the former and 11.9% of the latter group died by the end of the study period ( P = 0.0548). Malignancy was not associated with all‐cause mortality (HR: 1.3475, 95% CI: 0.7202–2.5214, P = 0.3507) but with malignancy‐associated mortality (HR: 3.9477, 95% CI: 1.6348–9.5331, P = 0.0023). Renal replacement therapy was not associated with mortality. Since malignancy greatly affects the prognosis, it must be taken into consideration when treating these patients.