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Selective Plasma Exchange for Critically Ill Patients Accompanied With Thrombocytopenia
Author(s) -
Nakae Hajime,
Fukuda Hirokazu,
Okuyama Manabu,
Igarashi Toshiko
Publication year - 2016
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/1744-9987.12464
Subject(s) - medicine , fibrinogen , albumin , prothrombin time , fresh frozen plasma , critically ill , coagulation , bilirubin , blood proteins , gastroenterology , platelet
Selective plasma exchange is a blood purification therapy in which simple plasma exchange is performed using a selective membrane plasma separator (pore size of 0.03 µm). Seven critically ill patients accompanied with thrombocytopenia were treated with selective plasma exchange using fresh frozen plasma. The total bilirubin levels and prothrombin time international normalized ratios decreased significantly after treatment. The total protein, albumin, and fibrinogen levels increased significantly after treatment. Selective plasma exchange may be a useful blood purification therapy for removing causal substances and retaining coagulation factors in patients accompanied with thrombocytopenia.