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Validating the Absolute Reliability of a Fat Free Mass Estimate Equation in Hemodialysis Patients Using Near‐Infrared Spectroscopy
Author(s) -
Kono Kenichi,
Nishida Yusuke,
Moriyama Yoshihumi,
Taoka Masahiro,
Sato Takashi
Publication year - 2015
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1111/1744-9987.12283
Subject(s) - medicine , hemodialysis , fat free mass , linear regression , dry weight , mean difference , dialysis , body weight , zoology , fat mass , mathematics , statistics , confidence interval , botany , biology
The assessment of nutritional states using fat free mass ( FFM ) measured with near‐infrared spectroscopy ( NIRS ) is clinically useful. This measurement should incorporate the patient's post‐dialysis weight (“dry weight”), in order to exclude the effects of any change in water mass. We therefore used NIRS to investigate the regression, independent variables, and absolute reliability of FFM in dry weight. The study included 47 outpatients from the hemodialysis unit. Body weight was measured before dialysis, and FFM was measured using NIRS before and after dialysis treatment. Multiple regression analysis was used to estimate the FFM in dry weight as the dependent variable. The measured FFM before dialysis treatment ( M w‐ FFM ), and the difference between measured and dry weight ( M w‐ D w) were independent variables. We performed Bland‐Altman analysis to detect errors between the statistically estimated FFM and the measured FFM after dialysis treatment. The multiple regression equation to estimate the FFM in dry weight was: D w‐ FFM = 0.038 + (0.984 × M w‐ FFM ) + (−0.571 × [ M w‐ D w]); R 2 = 0.99). There was no systematic bias between the estimated and the measured values of FFM in dry weight. Using NIRS , FFM in dry weight can be calculated by an equation including FFM in measured weight and the difference between the measured weight and the dry weight.