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Treatment outcome of craniopharyngioma: 18‐Year experience at a Hong Kong regional neurosurgical centre
Author(s) -
Chan David YuenChung,
Cheng Yue,
Lee Michael WingYan,
Pang Vincent KaiYuen,
Wong ChiKeung
Publication year - 2017
Publication title -
surgical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.109
H-Index - 10
eISSN - 1744-1633
pISSN - 1744-1625
DOI - 10.1111/1744-1633.12240
Subject(s) - medicine , craniopharyngioma , neurosurgery , surgery , perioperative , randomized controlled trial , retrospective cohort study
Aim The aim of the present study was to evaluate the treatment outcome of craniopharyngioma at a neurosurgery centre in Hong Kong over an 18‐year period. Patients and Methods The study design was a retrospective review of patients with craniopharyngioma. Clinical records of all patients with histologically‐confirmed craniopharyngioma during the period from January 1998 to December 2015 at a neurosurgery centre in Hong Kong were reviewed. Outcome measures included recurrence, morbidities and mortalities. Results From January 1998 to December 2015, 13 patients with histologically‐diagnosed craniopharyngioma were identified. Gross total resection (GTR) was achieved in 75 per cent (9/12) of primary craniopharyngiomas; a total of 25 per cent (3/12) had recurrence requiring reoperation, which was comparable to the 24.5 per cent reported in the literature. Morbidities included visual field defect (16.7 per cent), visual acuity deficit (8.3 per cent) and endocrinopathy (83.3 per cent). All patients with adjuvant radiotherapy in the present study had no tumour recurrence or progression. There was no perioperative mortality. Conclusion The treatment outcome of craniopharyngioma at a regional neurosurgical centre in Hong Kong had a recurrence rate comparable to the international standard. Consistent with other reported studies, postoperative morbidities are high with GTR. Further large‐scale, randomized, controlled trials are needed to demonstrate a superior long‐term outcome from a more conservative approach.