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Evaluation of the Role of Toxicological Data in Discriminating Between H 2 S Femoral Blood Concentration Secondary to Lethal poisoning and Endogenous H 2 S Putrefactive Production
Author(s) -
Barbera Nunziata,
Montana Angelo,
Indorato Francesca,
Arbouche Nadia,
Romano Guido
Publication year - 2017
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/1556-4029.13291
Subject(s) - putrefaction , endogeny , hydrogen sulfide , hypoxemia , poison control , physiology , forensic toxicology , toxicology , medicine , chemistry , emergency medicine , biology , chromatography , ecology , sulfur , organic chemistry
Hydrogen sulfide is a colorless gas and has a strong odor of rotten eggs. It is absorbed by the upper respiratory tract mucosa, and it causes histotoxic hypoxemia and respiratory depression by exerting an inhibitory effect on cytochrome oxidase. To evaluate the role of toxicological data in distinguishing between the H 2 S blood concentration secondary to lethal poisoning and the endogenous H 2 S produced during putrefaction, we compared the postmortem H 2 S concentrations of six fatal H 2 S poisoning cases (8.7–28.6 mg/L) with the postmortem concentrations of endogenous H 2 S of 12 subjects who died from other causes (traffic‐related deaths) (2.2–32.7 mg/L). These results will be of interest to the forensic community as it underlines the importance of considering circumstantial evidence along with the toxicological and pathological findings in the identification of H 2 S lethal poisoning.