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Determination of Inorganic Ion Profiles of Illicit Drugs by Capillary Electrophoresis
Author(s) -
Evans Elizabeth,
Costrino Carolina,
Lago Claudimir L.,
Garcia Carlos D.,
Roux Claude,
Blanes Lucas
Publication year - 2016
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/1556-4029.13175
Subject(s) - capillary electrophoresis , chemistry , chromatography , ionic bonding , designer drug , analytical chemistry (journal) , electrophoresis , ion , drug , pharmacology , organic chemistry , medicine
A portable capillary electrophoresis instrument with dual capacitively coupled contactless conductivity detection (C 4 D) was used to determine the inorganic ionic profiles of three pharmaceutical samples and precursors of two illicit drugs (contemporary samples of methylone and para‐methoxymethamphetamine). The LOD s ranged from 0.10 μmol/L to 1.25 μmol/L for the 10 selected cations, and from 0.13 μmol/L to 1.03 μmol/L for the eight selected anions. All separations were performed in less than 6 min with migration times and peak area RSD values ranging from 2 to 7%. The results demonstrate the potential of the analysis of inorganic ionic species to aid in the identification and/or differentiation of unknown tablets, and real samples found in illicit drug manufacture scenarios. From the resulting ionic fingerprint, the unknown tablets and samples can be further classified.