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Age Estimation in Living Egyptians Using Signal Joint T‐cell Receptor Excision Circle Rearrangement
Author(s) -
Ibrahim Samah F.,
Gaballah Iman F.,
Rashed Laila A.
Publication year - 2016
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/1556-4029.12988
Subject(s) - context (archaeology) , taqman , estimation , forensic science , forensic anthropology , population , medicine , standard error , demography , biology , statistics , gene , real time polymerase chain reaction , genetics , veterinary medicine , mathematics , geography , environmental health , economics , paleontology , management , archaeology , sociology
Age estimation is one of the challenges in forensic sciences. There are many techniques to estimate the age. Molecular biology approach is one of these techniques. Signal joint T‐cell receptor excision circles gene (sj TREC s), is one of this approach. We aimed to use sj TREC s as a suitable marker for age estimation among Egyptian population. TaqMan qPCR approach was used to quantify sj TREC levels in blood samples obtained from 153 healthy Egyptian individuals ranging from a few weeks to 70 years. Our results showed a significant negative correlation between sj TREC levels and age with p ≤ 0.05. Moreover, the individual's age can be determined through this formula Age = −30.671+ (−5.998 Y ) ( Y is dCtTBP − sj TREC ) with standard error ±7.35 years. Within the forensic context, sj TREC ' levels can be used to estimate the Egyptian individual's age accurately.