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Anaphylaxis After the Injection of Buprenorphine
Author(s) -
Boggs Cassie L.,
Ripple Mary G.,
Ali Zabiullah,
Brassell Melissa,
Levine Barry,
JuferPhipps Rebecca,
Doyon Suzanne,
Fowler David R.
Publication year - 2013
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/1556-4029.12161
Subject(s) - anaphylaxis , medicine , drug , buprenorphine , anaphylactic reactions , cause of death , time of death , intensive care medicine , anesthesia , pharmacology , medical emergency , allergy , immunology , opioid , disease , receptor
Cause of death rulings in cases when the concentration of a drug or drugs is higher than observed following therapeutic use are generally straightforward “drug deaths.” However, when toxicology testing identifies drug concentrations consistent with therapeutic use or detects no drugs at all, then the cause of death determination is more complicated. Given the rapidity and protean manifestations of anaphylaxis, it should be considered in deaths where no other cause of death is apparent in a suspected drug death. This article reports two cases where an anaphylactic reaction was observed following either the actual or alleged use of therapeutic formulations of buprenorphine intravenously.