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Health‐Related Quality of Life among Chronic Opioid Users, Nonchronic Opioid Users, and Nonopioid Users with Chronic Noncancer Pain
Author(s) -
Hayes Corey J.,
Li Xiaocong,
Li Chenghui,
Shah Anuj,
Kathe Niranjan,
Bhandari Naleen Raj,
Payakachat Nalin
Publication year - 2018
Publication title -
health services research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.706
H-Index - 121
eISSN - 1475-6773
pISSN - 0017-9124
DOI - 10.1111/1475-6773.12836
Subject(s) - medicine , opioid , chronic pain , propensity score matching , medical prescription , physical therapy , nursing , receptor
Objective Evaluate the association between opioid therapy and health‐related quality of life ( HRQ oL) in participants with chronic, noncancer pain ( CNCP ). Data Sources Medical Expenditure Panel Survey Longitudinal, Medical Conditions, and Prescription Files. Study Design Using a retrospective cohort study design, the Mental Health Component ( MCS 12) and Physical Health Component ( PCS 12) scores of the Short Form‐12 Version 2 were assessed to measure mental and physical HRQ oL. Data Collection Chronic, noncancer pain participants were classified as chronic, nonchronic, and nonopioid users. One‐to‐one propensity score matching was employed to match chronic opioid users to nonchronic opioid users plus nonchronic opioid users and chronic opioid users to nonopioid users. Principal Findings A total of 5,876 participants were identified. After matching, PCS 12 was not significantly different between nonchronic versus nonopioid users ( LSM Diff = −0.98, 95% CI : −2.07, 0.10), chronic versus nonopioid users ( LSM Diff = −2.24, 95% CI : −4.58, 0.10), or chronic versus nonchronic opioid users ( LSM Diff = −2.23, 95% CI : −4.53, 0.05). Similarly, MCS 12 was not significantly different between nonchronic versus nonopioid users ( LSM Diff = 0.76, 95% CI : −0.46, 1.98), chronic versus nonopioid users ( LSM Diff = 1.08, 95% CI : −1.26, 3.42), or chronic versus nonchronic opioid users ( LSM Diff = −0.57, 95% CI : −2.90, 1.77). Conclusions Clinicians should evaluate opioid use in participants with CNCP as opioid use is not correlated with better HRQ oL.