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Therapeutic endometrial regeneration: clinical application of bone marrow‐derived stem cells
Author(s) -
Taylor HS
Publication year - 2020
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/1471-0528.16088
Subject(s) - stem cell , regeneration (biology) , bone marrow , bone marrow stem cell , content (measure theory) , computer science , information retrieval , psychology , medicine , biology , microbiology and biotechnology , mathematics , mathematical analysis
Endometrial dysfunction is a widespread problem that can result in both infertility and pregnancy loss. Perhaps the most extreme variant of endometrial dysfunction is failure to generate sufficient endometrial tissue, resulting in a thin endometrium incapable of supporting embryo implantation. In Asherman's syndrome this is due to destruction of the endometrium, typically after trauma, with subsequent scarring and fibrosis. The etiology of endometrial atrophy in the absence of Asherman's syndrome is generally unknown.