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Microbicides and their potential as a catalyst for multipurpose sexual and reproductive health technologies
Author(s) -
Abdool Karim Q,
Baxter C,
Abdool Karim S
Publication year - 2014
Publication title -
bjog: an international journal of obstetrics and gynaecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.157
H-Index - 164
eISSN - 1471-0528
pISSN - 1470-0328
DOI - 10.1111/1471-0528.12843
Subject(s) - microbicides for sexually transmitted diseases , reproductive health , microbicide , human immunodeficiency virus (hiv) , medicine , clinical trial , environmental health , virology , health services , population
There is an urgent need for technologies to prevent sexual acquisition of HIV infection in young women in sub‐Saharan Africa. After two decades of 11 pivotal trials of seven products, anti‐retroviral‐based topical microbicides are showing promise. Building on the CAPRISA 004 trial findings, several trials of new anti‐viral agents, novel delivery mechanisms and combination/multipurpose products that address challenges of adherence and meet the sexual and reproductive health needs of men and women, including preventing HIV infection, are underway.