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Camel milk ameliorates the coagulopathy in streptozotocin diabetic rat model
Author(s) -
Korish Aida A,
Abdel Gader Abdel Galil M,
Alhaider Abdulqader A
Publication year - 2015
Publication title -
international journal of dairy technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 53
eISSN - 1471-0307
pISSN - 1364-727X
DOI - 10.1111/1471-0307.12168
Subject(s) - streptozotocin , antithrombotic , fibrinogen , medicine , platelet , diabetes mellitus , platelet aggregation , coagulation , endocrinology
This study investigated the effect of camel milk ( CM ) on blood coagulation in streptozotocin ( STZ ) – induced diabetic rats. Rats were split into four groups: controls, healthy rats treated with CM , STZ ‐induced diabetic rats and diabetic rats treated with CM . The untreated diabetic animals showed marked hyperglycemia, significant hypofibrinogenemia and inhibition of platelet aggregation. CM treatment ameliorated hyperglycemia, blocked fibrinogen consumption and restored platelet aggregation. This antithrombotic action of CM offers further beneficial effects in addition to its known hypoglycemic action in diabetes. The responsible antithrombotic component(s) is a potential nutraceutical that needs further studies.