Immunomodulatory and antioxidative potential of herb (  P ueraria tuberosa ) in mice using milk as the carrier | Zendy

Sawale Pravin Digambar | Zendy; Singh Ram Ran Bijoy | Zendy; Kapila Suman | Zendy; Arora Sumit | Zendy; Rastogi Subha | Zendy; Rawat Ajay Kumar Singh | Zendy

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Immunomodulatory and antioxidative potential of herb ( P ueraria tuberosa ) in mice using milk as the carrier

Author(s) -

Sawale Pravin Digambar,

Singh Ram Ran Bijoy,

Kapila Suman,

Arora Sumit,

Rastogi Subha,

Rawat Ajay Kumar Singh

Publication year - 2013

Publication title -

international journal of dairy technology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.061

H-Index - 53

eISSN - 1471-0307

pISSN - 1364-727X

DOI - 10.1111/1471-0307.12011

Subject(s) - thiobarbituric acid , antibody , chemistry , tbars , glutathione , biology , immunology , food science , biochemistry , antioxidant , lipid peroxidation , enzyme

Eighteen healthy male mice were divided into three equal groups and given specific diets for a period of 28 days: Group M were fed a normal synthetic diet ( NSD ) and milk; Group P were fed NSD and P ueraria tuberosa ( PT ) extract (0.4%), while the diet of group PM was NSD supplemented with PT extract (0.4%) and milk. The phagocytic activity and immunoglobulin A (in intestines) and immunoglobulin G (serum) levels increased significantly in comparison with group M in PT supplemented groups after a period of 28 days. Group P and Group PM showed significantly higher reduced glutathione level and significantly lowered thiobarbituric acid reactive substances levels in liver and red blood cells as compared to control.

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