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Immunomodulatory and antioxidative potential of herb ( P ueraria tuberosa ) in mice using milk as the carrier
Author(s) -
Sawale Pravin Digambar,
Singh Ram Ran Bijoy,
Kapila Suman,
Arora Sumit,
Rastogi Subha,
Rawat Ajay Kumar Singh
Publication year - 2013
Publication title -
international journal of dairy technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.061
H-Index - 53
eISSN - 1471-0307
pISSN - 1364-727X
DOI - 10.1111/1471-0307.12011
Subject(s) - thiobarbituric acid , antibody , chemistry , tbars , glutathione , biology , immunology , food science , biochemistry , antioxidant , lipid peroxidation , enzyme
Eighteen healthy male mice were divided into three equal groups and given specific diets for a period of 28 days: Group M were fed a normal synthetic diet ( NSD ) and milk; Group P were fed NSD and P ueraria tuberosa ( PT ) extract (0.4%), while the diet of group PM was NSD supplemented with PT extract (0.4%) and milk. The phagocytic activity and immunoglobulin A (in intestines) and immunoglobulin G (serum) levels increased significantly in comparison with group M in PT supplemented groups after a period of 28 days. Group P and Group PM showed significantly higher reduced glutathione level and significantly lowered thiobarbituric acid reactive substances levels in liver and red blood cells as compared to control.