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A deep‐sea bacterium related to coastal marine pathogens
Author(s) -
Lasa Aide,
Auguste Ma,
Lema Alberto,
Oliveri Caterina,
Borello Alessio,
Taviani Elisa,
Bonello Guido,
Doni Lapo,
Millard Andrew D.,
Bruto Maxime,
Romalde Jesus L.,
Yakimov Michail,
Balbi Teresa,
Pruzzo Carla,
Canesi Laura,
Vezzulli Luigi
Publication year - 2021
Publication title -
environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.954
H-Index - 188
eISSN - 1462-2920
pISSN - 1462-2912
DOI - 10.1111/1462-2920.15629
Subject(s) - biology , pacific oyster , mytilus , vibrio , crassostrea , oyster , mediterranean sea , marine bacteriophage , shellfish , ecology , virulence , zoology , microbiology and biotechnology , bacteria , mediterranean climate , gene , aquatic animal , fishery , genetics , fish <actinopterygii>
Summary Evolution of virulence traits from adaptation to environmental niches other than the host is probably a common feature of marine microbial pathogens, whose knowledge might be crucial to understand their emergence and pathogenetic potential. Here, we report genome sequence analysis of a novel marine bacterial species, Vibrio bathopelagicus sp. nov., isolated from warm bathypelagic waters (3309 m depth) of the Mediterranean Sea. Interestingly, V. bathopelagicus sp. nov. is closely related to coastal Vibrio strains pathogenic to marine bivalves. V. bathopelagicus sp. nov. genome encodes genes involved in environmental adaptation to the deep‐sea but also in virulence, such as the R5.7 element, MARTX toxin cluster, Type VI secretion system and zinc‐metalloprotease, previously associated with Vibrio infections in farmed oysters. The results of functional in vitro assays on immunocytes (haemocytes) of the Mediterranean mussel Mytilus galloprovincialis and the Pacific oyster Crassostrea gigas, and of the early larval development assay in Mytilus support strong toxicity of V. bathopelagicus sp. nov. towards bivalves. V. bathopelagicus sp. nov., isolated from a remote Mediterranean bathypelagic site, is an example of a planktonic marine bacterium with genotypic and phenotypic traits associated with animal pathogenicity, which might have played an evolutionary role in the origin of coastal marine pathogens.