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Regulation of pro‐σ K activation: a key checkpoint in Bacillus subtilis sporulation
Author(s) -
Sun Gaohui,
Yang Moua,
Jiang Longguang,
Huang Mingdong
Publication year - 2021
Publication title -
environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.954
H-Index - 188
eISSN - 1462-2920
pISSN - 1462-2912
DOI - 10.1111/1462-2920.15415
Subject(s) - bacillus subtilis , biology , spore , key (lock) , microbiology and biotechnology , bacteria , computational biology , genetics , ecology
Summary The Gram‐positive bacterium Bacillus subtilis initiates the sporulation process under conditions of nutrient limitation. Here, we review related work in this field, focusing on the protein processing of the pro‐σ K activation. The purpose of this review is to illustrate the mechanism of pro‐σ K activation and provide structural insights into the regulation of spore production. Sporulation is not only important in basic science but also provides mechanistic insight for bacterial control in applications in, e.g., food industry.

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