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Oral cavity contains distinct niches with dynamic microbial communities
Author(s) -
Xu Xin,
He Jinzhi,
Xue Jing,
Wang Yan,
Li Kun,
Zhang Keke,
Guo Qiang,
Liu Xianghong,
Zhou Yuan,
Cheng Lei,
Li Mingyun,
Li Yuqing,
Li Yan,
Shi Wenyuan,
Zhou Xuedong
Publication year - 2015
Publication title -
environmental microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.954
H-Index - 188
eISSN - 1462-2920
pISSN - 1462-2912
DOI - 10.1111/1462-2920.12502
Subject(s) - biology , ecological niche , dentition , microbiome , oral cavity , saliva , oral microbiome , niche , ecology , habitat , phylogenetic tree , metagenomics , zoology , evolutionary biology , genetics , dentistry , gene , medicine , paleontology , biochemistry
Summary Microbes colonize human oral surfaces within hours after delivery. During postnatal development, physiological changes, such as the eruption of primary teeth and replacement of the primary dentition with permanent dentition, greatly alter the microbial habitats, which, in return, may lead to community composition shifts at different phases in people's lives. By profiling saliva, supragingival and mucosal plaque samples from healthy volunteers at different ages and dentition stages, we observed that the oral cavity is a highly heterogeneous ecological system containing distinct niches with significantly different microbial communities. More importantly, the phylogenetic microbial structure varies with ageing. In addition, only a few taxa were present across the whole populations, indicating a core oral microbiome should be defined based on age and oral niches.