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Moderate‐to‐high normal levels of thyrotropin is a risk factor for urinary incontinence and an unsuitable quality of life in women over 65 years
Author(s) -
CuevasRomero Estela,
SánchezCardiel Angélica,
ZamoraGallegos Angélica M.,
CruzLumbreras Rosalía,
CoronaQuintanilla Dora L.,
Castelán Francisco,
MartínezGómez Margarita
Publication year - 2017
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1111/1440-1681.12788
Subject(s) - urinary incontinence , medicine , quality of life (healthcare) , urology , risk factor , urinary system , endocrinology , physiology , nursing
Summary The present study aimed to investigate the relationship between normal serum concentrations of thyrotropin ( TSH ) and urinary incontinence ( IU ), urinary infections, and quality of life in old women. Euthyroid post‐menopausal women without sarcopenia, estrogen replacement, emotional illness, and/or cancer were enrolled as participants. Anthropometric indicators, serum glucose and estradiol, and thyroid profile were measured. Sociodemographic, clinical, physical activity, and quality of life ( SF ‐36) surveys were applied. One‐hour pad test and International Consultation on Incontinence Questionnaire Short Form ( ICIQ ‐ SF ) were used to determine UI . Urinalysis was also done. In agreement with results from the pad test (cut‐off point ≥1.4 g), the ICIQ ‐ SF reveled approximately 50% of incontinent women. A high percentage of women had moderate–high bacteriuria and urinary infections. Logistic regression analysis showed that age is a risk factor for both UI and urinary infection. Diabetes, number of pregnancies or childbirths, urinary infections, and bacteriuria did not influence the presence of UI . To allocate women into four groups according to their age (<65 or ≥65 years old) and TSH concentrations (0.3‐1.9 or 2‐10 μUI/mL), we found that moderate‐to‐high normal levels of TSH is a risk factor for UI and a worse quality of life in the oldest women. Our results highlight the profit of measuring TSH concentrations in post‐menopausal women.