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Epidemiological study on the relationship between toxin production and psm‐mec mutations in MRSA isolates in Thailand
Author(s) -
Tabuchi Fumiaki,
Lulitad Aroonlug,
Lulitad Viraphong,
Thunyaharn Sudaluck,
Kaito Chikara
Publication year - 2020
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/1348-0421.12764
Subject(s) - sccmec , microbiology and biotechnology , biology , staphylococcus aureus , toxin , methicillin resistant staphylococcus aureus , bacteria , genetics
In this present study, we investigated the phenol‐soluble modulin ( psm‐mec ) mutations, the staphylococcal cassette chromosome mec (SCC mec ) types, and toxin production in 102 methicillin‐resistant Staphylococcus aureus (MRSA) isolates from the northeast and central regions of Thailand. The MRSA isolates carrying ‐7T>C psm‐mec in Type II SCC mec ( n = 18) and the MRSA isolates carrying no psm‐mec in Type IV ( n = 8) or Type IX SCC mec ( n = 4) had higher hemolytic activity against sheep erythrocytes than MRSA isolates carrying intact psm‐mec in Type III SCC mec ( n = 34), but MRSA isolates carrying no psm‐mec in Type I SCC mec ( n = 27) did not.