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Species distribution, virulence factors and antimicrobial resistance of Acinetobacter spp. isolates from dogs and cats: a preliminary study
Author(s) -
Kimura Yui,
Harada Kazuki,
Shimizu Takae,
Sato Tomomi,
Kajino Akari,
Usui Masaru,
Tamura Yutaka,
Tsuyuki Yuzo,
Miyamoto Tadashi,
Ohki Asami,
Watarai Masahisa
Publication year - 2018
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/1348-0421.12601
Subject(s) - ciprofloxacin , acinetobacter baumannii , biology , microbiology and biotechnology , gentamicin , acinetobacter , virulence , antimicrobial , antibiotic resistance , drug resistance , antibiotics , bacteria , gene , pseudomonas aeruginosa , genetics
In this study, the prevalence of virulence factors and antimicrobial resistance among 67 Acinetobacter spp. isolates, consisting of 21 Acinetobacter baumannii and 46 non‐ baumannii Acinetobacter obtained from companion animals, was investigated. PCR analysis showed that the most prevalent virulence gene was afa/draBC (29.9%), followed by papC (22.4%) and cvaC (20.9%). Antimicrobial susceptibility testing revealed that resistance to gentamicin (14.9%) and ciprofloxacin (11.9%) was relatively prevalent. Five gentamicin‐ and/or ciprofloxacin‐resistant A. baumannii strains were assigned to ST25, ST149, ST164, ST203 and ST1198. All ciprofloxacin‐resistant isolates harbored point mutations in gyrA and/or parC . To the best of our knowledge, this is the first report of preliminary monitoring of animal‐origin Acinetobacter spp. in Japan.