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Sequence determination of a new parrot bornavirus‐5 strain in Japan: implications of clade‐specific sequence diversity in the regions interacting with host factors
Author(s) -
Komorizono Ryo,
Makino Akiko,
Horie Masayuki,
Honda Tomoyuki,
Tomonaga Keizo
Publication year - 2016
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/1348-0421.12385
Subject(s) - clade , biology , phylogenetic tree , host (biology) , phylogenetics , strain (injury) , evolutionary biology , sequence (biology) , genetics , sequence analysis , virology , gene , anatomy
In this study, the genome sequence of a new parrot bornavirus‐5 (PaBV‐5) detected in Eclectus roratus was determined. Phylogenetic analysis showed that the genus Bornavirus is divided into three major clades and that PaBV‐5 belongs to clade 2, which contains avian viruses that exhibit infectivity to mammalian cells. Sequence comparisons of the regions known to interact with host factors indicated that the clade 2 avian viruses possess sequences intermediate between the clade 1 mammalian viruses and the clade 3 avian viruses, suggesting that the identified regions might contribute to the differences in virological properties between the three clades.