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Issue Information – Cover
Publication year - 2016
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/1348-0421.12308
Subject(s) - biology , retinal , inner plexiform layer , antibody , cover (algebra) , immunofluorescence , outer plexiform layer , immunology , pathology , microbiology and biotechnology , medicine , biochemistry , mechanical engineering , engineering
Confocal immunofluorescence image of retinal microglial cells from a C57BL/6J mouse undergoing non‐ocular conditions: immunosuppression (by cyclophosphamide) and peripheral inflammation (sublethal colitis chemically‐induced with dextran sulphate sodium salt), both administered systemically. Microglial cells (Iba1 positive cells, in green) present an activated state, with an elongated soma and immunoreactivity against MHCIIRT1B antibody (red fluorescence, coexpression is seen in yellow). Cells are spread through different retinal layers (outer plexiform, inner nuclear, inner plexiform and ganglion cell layers). Non‐specific immunoreactivity of the secondary antibody (in red) to blood vessels is also observed. Microbiol Immunol : 60:617–625. Article link here .