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Five cases of new‐onset pemphigus following vaccinations against coronavirus disease 2019
Author(s) -
Corrá Alberto,
Barei Francesca,
Genovese Giovanni,
Zussino Martina,
Spigariolo Cristina B.,
Mariotti Elena B.,
Quintarelli Lavinia,
Verdelli Alice,
Caproni Marzia,
Marzano Angelo V.
Publication year - 2023
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.16554
Subject(s) - pemphigus , pemphigus vulgaris , medicine , autoantibody , immunology , disease , desmoglein , pathogenesis , covid-19 , vaccination , desmoglein 3 , dermatology , antibody , pathology , infectious disease (medical specialty)
Pemphigus is a group of blistering disorders characterized by the formation of intraepithelial blisters in skin and mucous membranes induced by the binding of circulating autoantibodies to intercellular adhesion molecules. The pathogenesis is complex and not fully understood; however, genetic predisposition and various triggers are widely accepted as key factors in pemphigus development. A few cases of new‐onset pemphigus following coronavirus disease 2019 (COVID‐19) vaccination have already been published. The present paper reports a total of two cases of pemphigus foliaceous and three cases of pemphigus vulgaris that occurred following vaccinations against COVID‐19, with anamnestic, clinical, and diagnostic data collection suggesting assumptions over a possible causal correlation.

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