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Cluster of pregnancy‐associated melanoma: A case report and brief update
Author(s) -
Van Rooij Nicholas,
Adams Agnieszka,
De’Ambrosis Brian,
Nathan Vaishnavi,
Hayward Nicholas,
Whiteman David
Publication year - 2020
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.15455
Subject(s) - medicine , incidence (geometry) , pregnancy , melanoma , dermatology , post partum , postpartum period , obstetrics , genetics , physics , cancer research , optics , biology
Melanoma incidence is increasing globally with Australia having the highest incidence in the world. Pregnancy‐associated melanoma is recognized in the published work; however, significant knowledge deficiencies exist. We present the case of a 34‐year‐old woman with dysplastic nevus syndrome who over a 15‐year period developed a total of nine melanomas, with eight clustered around an 18‐month peri‐ to post‐partum period. The first eight lesions were in situ with the ninth lesion invasive. No metastatic disease was observed over the 18‐year follow‐up period. This case identifies the potential sensitivity of a subset of melanomas to pregnancy‐related factors, with particular relevance to the development of lesions in the post‐partum period. We suggest that patients with a history of any documented melanoma risk factors, particularly dysplastic nevus syndrome, require close monitoring especially during pregnancy and early post‐partum.