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Survey of Japanese dermatological vasculitis specialists on cases of cutaneous arteritis (cutaneous polyarteritis nodosa)
Author(s) -
Ikeda Takaharu,
Kawakami Tamihiro,
Arimura Yoshihiro,
Ishiguro Naoko,
Ishizu Akihiro,
Ito Fuyu,
ItoIhara Toshiko,
Okiyama Naoko,
Ono Sachiko,
Suzuki Kazuo,
Sugawara Koji,
Seishima Mariko,
Kodera Masanari,
Tanaka Maiko,
Hasegawa Minoru,
Furukawa Fukumi,
Yamaguchi Yukie,
Yoshizaki Ayumi
Publication year - 2020
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.15273
Subject(s) - medicine , polyarteritis nodosa , vasculitis , arteritis , dermatology , systemic vasculitis , giant cell arteritis , myalgia , cerebral vasculitis , disease
We developed a questionnaire to examine the findings of cutaneous arteritis among dermatological specialists experienced in vasculitis as certified by the Committee for guidelines for the management of vasculitis and vascular disorders of the Japanese Dermatological Association. We sent a questionnaire to 12 dermatological facilities identified through the revised Committee for guidelines for the management of vasculitis and vascular disorders of the Japanese Dermatological Association. Retrospective data obtained from 84 patients at the 12 dermatological facilities between 2012 January 2016 December were evaluated. The 84 patients were categorized into two groups, a systemic steroid treatment group (group 1, n = 52) and a no systemic steroid treatment group (group 2, n = 32). C‐reactive protein in group 1 patients was significantly higher than that in group 2 patients. Frequency of fever, arthritis, myalgia‐ and peripheral neuropathy in group 1 was significantly higher than that in group 2. We propose that these symptoms could serve as early markers for the transfer from cutaneous arteritis to systemic polyarteritis nodosa. We further suggest that patients who are subsequently associated with cerebral hemorrhage and infarction, who are originally diagnosed as having cutaneous arteritis, could progress to systemic polyarteritis nodosa. The study demonstrated that it is important for dermatologists to detect these findings early in order to establish an accurate diagnosis and a timely treatment.