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Successful treatment of chromoblastomycosis caused by Fonsecaea pedrosoi using imiquimod
Author(s) -
Belda Walter,
Criado Paulo Ricardo,
Passero Luiz Felipe Domingues
Publication year - 2020
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.15225
Subject(s) - chromoblastomycosis , imiquimod , terbinafine , itraconazole , dermatology , medicine , antifungal
Chromoblastomycosis (CBM) is a fungal infection caused by fungi belonging to the order Chaetothyriales , and caused mainly by Fonsecaea pedrosoi . The classic treatment, based on itraconazole and/or terbinafine as well as physical approaches, is considered complex and ineffective due to the high rate of relapses. Thus, new strategies are needed to manage CBM; in this regard, the present work reports the evolution of lesions in patients successfully treated with imiquimod. Of note, classic treatment was not effective in healing the lesions of two of them, but single topical treatment with imiquimod healed the lesions.