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Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms
Author(s) -
Higashi Yuko,
Baba Naoko,
Yoshimine Haruhito,
Sakaguchi Ikuyo,
Kanekura Takuro
Publication year - 2020
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.15175
Subject(s) - medicine , fulminant , eosinophilia , interstitial nephritis , nephritis , hypersensitivity reaction , drug allergy , drug , dermatology , immunology , kidney , pharmacology
Drug‐induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe hypersensitivity drug reaction affecting the skin and multiple internal organ systems. We report a 47‐year‐old man with DIHS/DRESS and comorbidities (fulminant type 1 diabetes mellitus, valsartan‐induced photosensitivity, vitiligo and acute interstitial nephritis). Although acute interstitial nephritis usually appears in the early phase, his is a rare case of acute interstitial nephritis more than 2 years after the onset of DIHS/DRESS.