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Ungual hyalohyphomycosis caused by Fusarium proliferatum in an immunocompetent patient
Author(s) -
Noguchi Hiromitsu,
Hiruma Masataro,
Matsumoto Tadahiko,
Kano Rui,
Ihn Hironobu
Publication year - 2017
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.13570
Subject(s) - fusarium proliferatum , terbinafine , hypha , concomitant , medicine , nail (fastener) , thickening , nail disease , fusarium , dermatology , pathology , biology , botany , surgery , antifungal , paronychia , chemistry , materials science , itraconazole , polymer science , metallurgy
The patient was a 73‐year‐old healthy female farmer who had been treated with terbinafine for 25.5 months by a primary physician. She exhibited a discoloration and thickening of the right big toenail. She had no concomitant paronychia. Direct microscopy revealed chlamydoconidia and hyphae, and periodic acid‐Schiff stained nail specimen showed septate hyphae. On the basis of these morphological features and gene analysis, the final diagnosis was ungual hyalohyphomycosis caused by Fusarium proliferatum . Topical application of 10% efinaconazole solution cured the disease in 10 months.