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Vascular network tightly enclosing lesions of molluscum contagiosum: Basket‐like capillaries of molluscum
Author(s) -
Horiguchi Yuji,
Horiguchi Junshi,
Maeno Kenichiro
Publication year - 2017
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.13519
Subject(s) - molluscum contagiosum , vascular network , virology , dermatology , medicine , anatomy
Immunohistochemical studies of one typical and two atypical cases of molluscum contagiosum with anti‐ CD 34 monoclonal antibodies showed a tightly enclosing fine vasculature around the lesional masses of the disease. The thin interstitial septa between the lobules of the molluscum lesions also contained abundant endothelium. An electron microscopic study of a pinched‐off lesion of common molluscum contagiosum demonstrated that the tightly enclosing blood vessels lacked muscle layers, suggesting that they were capillaries, being a distance of several hundred nanometers from the basal cells of the molluscum mass. A 3D constructed image of the vasculature confirmed a network of the vessels. These tightly enclosing vascular networks around the lesions of molluscum contagiosum support the rapid growth of this disease.