Premium
Two cases of genital neutrophilic sebaceous adenitis
Author(s) -
Tohyama Mikiko,
Matsumoto Keiko,
Sayama Koji
Publication year - 2016
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.13448
Subject(s) - vulva , apocrine , dermatology , meibomian gland , medicine , sebaceous gland , eyelid , sex organ , glans penis , glans , demodex , vulvitis , pathology , penis , anatomy , biology , surgery , gynecology , vaginitis , botany , genetics , mite
Sebaceous glands without a follicular structure are present in the eyelid margin (meibomian glands), lip, glans penis and vulva. Inflammatory disease of a sebaceous gland lacking follicles is rare, except for meibomitis. We report the first two cases of vulval sebaceous adenitis. Painful, yellowish‐orange papules/nodules recurred at the vulval mucocutaneous junction or mucosa during the luteal phase of the menstrual cycle. Histopathologically, a dense neutrophilic infiltration was observed within the sebaceous ducts. In both cases, oral minocycline improved the condition. They had been treated with antiherpetic agents. It is possible that women diagnosed with recurrent genital herpes have genital neutrophilic sebaceous adenitis.