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New aspects of the clinicopathological features and treatment of mycosis fungoides and Sézary syndrome
Author(s) -
Furue Masutaka,
Kadono Takafumi
Publication year - 2015
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.13083
Subject(s) - mycosis fungoides , dermatology , medicine , pathology , lymphoma
Mycosis fungoides and Sézary syndrome are T‐helper (Th)2‐skewed cutaneous lymphomas. The clinical course of mycosis fungoides is classically indolent, manifesting as patches, plaques and tumors. Along with their progression, Th2 dominance tends to be accelerated. In this review, we discuss the epidemiology, clinicopathogenetic features and therapeutic approaches in mycosis fungoides and Sézary syndrome.