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Pirfenidone‐induced photoleukomelanoderma in a patient with idiopathic pulmonary fibrosis
Author(s) -
Tsuruta Aoi,
Washio Ken,
Fukunaga Atsushi,
Nishigori Chikako
Publication year - 2016
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.13009
Subject(s) - pirfenidone , idiopathic pulmonary fibrosis , medicine , pulmonary fibrosis , fibrosis , intensive care medicine , lung
This is believed to be the first report of pirfenidone‐induced photoleukomelanoderma. We discuss the male predominance of photosensitivity induced by pirfenidone. Both ultraviolet ( UV)‐A and UV‐B seemed to be included within the action spectrum of this disorder. Although pirfenidone is a key drug for the treatment of idiopathic pulmonary fibrosis, clinicians should be aware of the high prevalence of photosensitivity and perform sufficient patient education for comprehensive photoprotection before prescription.