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Cutaneous lesions of Kikuchi's disease: Evolution of histopathological findings
Author(s) -
Kanno Kyoko,
MinamiHori Masako,
IshidaYamamoto Akemi,
Komura Keiji,
Oikawa Kensuke,
Miyokawa Naoyuki,
Iizuka Hajime
Publication year - 2014
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.12557
Subject(s) - histopathology , pathology , medicine , lymph node , dermatology , disease , biopsy
Abstract We report a 38‐year‐old male patient who presented with cutaneous lesions mimicking widespread discoid lupus erythematosus with high‐grade fever, arthralgia and lymphadenopathy. Additional lymph node and skin biopsies, however, revealed karyorrhectic debris without neutrophils and numerous CD 68‐positive cells, a characteristic finding of Kikuchi's disease ( KD ). Comparing skin biopsies on different occasions, we could see different forms of histopathology. The histopathology of skin lesions of KD may vary during the clinical course, which may reflect the stage of the disease.