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Proliferative fasciitis mimicking a sarcoma in a child: A case report
Author(s) -
Yamaga Kensaku,
Shomori Kohei,
Yamashita Hideki,
Endo Koji,
Takeda Chikako,
Minamizaki Takeshi,
Yoshida Haruhiko,
Teshima Ryota,
Ito Hisao
Publication year - 2014
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.12384
Subject(s) - nodular fasciitis , vimentin , sarcoma , cytokeratin , pathology , medicine , epithelioid sarcoma , metastasis , fasciitis , soft tissue sarcoma , magnetic resonance imaging , fibrosarcoma , immunohistochemistry , soft tissue , cancer , radiology
Proliferative fasciitis ( PF ) is a benign, discrete proliferation of fibroblasts or myofibroblasts in soft tissue. Proliferative fasciitis mostly occurs in adults and is often confused with a sarcoma because of its rapid growth and peculiar histological features. We report a case of PF mimicking a sarcoma which developed in a 13‐year‐old boy, who noticed a painful tumor, with gradual enlargement, in his right lower leg. Magnetic resonance imaging revealed that the tumor measured 34 mm × 20 mm × 41 mm and was located in the subcutaneous tissue. The tumor was surgically resected. Pathologically, the tumor was composed of a proliferation of atypical spindle cells, admixed with larger ganglion‐like cells. Immunohistochemically, the tumor cells were positive for vimentin, cytokeratin, smooth muscle actin, HHF ‐35 and F li‐1. The tumor was subsequently diagnosed as a PF , although it was difficult to differentiate from a sarcoma. Five years after surgery, the postoperative course has been uneventful with no recurrence or metastasis.