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Case of phaeohyphomycosis producing sporotrichoid lesions
Author(s) -
Hasei Maki,
Takeda Kiminobu,
Anzawa Kazushi,
Nishibu Akiko,
Tanabe Hiroshi,
Mochizuki Takashi
Publication year - 2013
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/1346-8138.12193
Subject(s) - medicine , polyarthritis , granuloma , lesion , phaeohyphomycosis , dermis , biopsy , cyst , terbinafine , dapsone , scedosporium apiospermum , pathology , voriconazole , dermatology , arthritis , itraconazole , antifungal , immunology
Abstract A 90‐year‐old Japanese woman, taking prednisolone (5–10 mg/day) for polyarthritis, presented to our hospital with multiple subcutaneous lesions on her left arm in 2009. Her history included excision of a phaeomycotic cyst on the left middle finger in 2007. There were three subcutaneous nodules approximately 15 mm in diameter around her left wrist and a large soft cystic lesion measuring 80 mm × 60 mm on her left elbow. A granuloma with neutrophilic infiltration was detected in the deep dermis of a biopsy specimen. Chains composed of round brown cells and short pseudomycelia were found in the granuloma. Fungal cultures from the samples confirmed E xophiala sp. to be the causative agent. Treatment with terbinafine and local hyperthermia seemed effective as all the lesions tended to subside. However, the patient died due to pneumonia approximately 1 month after commencement of therapy.