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2004 Irving Sigal Young Investigator Award
Author(s) -
Weissman Jonathan S.,
O'Shea Erin K.
Publication year - 2004
Publication title -
protein science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.353
H-Index - 175
eISSN - 1469-896X
pISSN - 0961-8368
DOI - 10.1110/ps.041134604
Subject(s) - history
fore both of us joined the faculty at UCSF. Ostensibly our specific research interests diverged: E.K.O. worked on tran- scription and signal transduction, and J.S.W. worked on chaperonin-mediated protein folding and prion-based inher- itance. However, we both retained the common goal of go- ing beyond simple phenomenological models to explain complex cellular behaviors. We also both naturally gravi- tated to using the common bakers yeast Saccharomyces cere- visiae as a model organism because its simplicity and tech- nical advantages provided the most hopeful platform for such approaches, especially after the genome sequence of S.