A High CMRR and Sub-pA Current Sensing Front-End for Biomedical Applications in FD-SOI | Zendy

Xingchen Xu | Zendy; Fengling Qin | Zendy; Silong Chen | Zendy; Xin Lin | Zendy; Shilong Chen | Zendy; Zhiqiang Li | Zendy

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A High CMRR and Sub-pA Current Sensing Front-End for Biomedical Applications in FD-SOI

Author(s) -

Xingchen Xu,

Fengling Qin,

Silong Chen,

Xin Lin,

Shilong Chen,

Zhiqiang Li

Publication year - 2025

Publication title -

ieee access

Language(s) - English

Resource type - Magazines

SCImago Journal Rank - 0.587

H-Index - 127

eISSN - 2169-3536

DOI - 10.1109/access.2025.3621766

Subject(s) - aerospace , bioengineering , communication, networking and broadcast technologies , components, circuits, devices and systems , computing and processing , engineered materials, dielectrics and plasmas , engineering profession , fields, waves and electromagnetics , general topics for engineers , geoscience , nuclear engineering , photonics and electrooptics , power, energy and industry applications , robotics and control systems , signal processing and analysis , transportation

This paper presents a high-resolution analog front-end (AFE) circuit. The AFE integrates a low-noise current amplifier and a second-order delta-sigma modulator (DSM). Implemented in 22nm Fully Depleted Silicon-On-Insulator (FD-SOI) technology, the amplifier achieves a bandwidth of 16MHz with gain up to MΩ-range at 10 kHz. The measured input current noise densities reach 38.56 fA/√Hz at 1 Hz and 21.28 fA/√Hz at 10 Hz, while maintaining a common-mode rejection ratio (CMRR) of 162 dB. The DSM operates under 1.2 V supply voltage with 12.8 MHz sampling frequency, demonstrating 91.3 dB SNDR, 13.9-bit ENOB, and 160.44 dB FoMSNDR at 3.66 mW power consumption. Benefiting from the noise suppression and interference immunity of FD-SOI technology, the proposed design demonstrates low-noise characteristics, low-power consumption, and an enhanced CMRR. It addresses engineering implementation pain points such as "high noise interference, high power consumption, and insufficient accuracy" in weak current signal detection, and provides a highly reliable hardware solution for signal acquisition needs in fields including biomedical applications, industrial sensing, and precision instruments.

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