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Concomitant cocrystal and salt: no interconversion in the solid state
Author(s) -
Losev Evgeniy A.,
Boldyreva Elena
Publication year - 2019
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 17
ISSN - 2053-2296
DOI - 10.1107/s2053229619001372
Subject(s) - cocrystal , concomitant , salt (chemistry) , solid state , state (computer science) , chemistry , materials science , computer science , mathematics , organic chemistry , algorithm , molecule , hydrogen bond , statistics
A cocrystal and a molecular salt of β‐alanine and dl ‐tartaric acid, C 3 H 8 NO 2 + ·C 4 H 4 O 6 − , of the same chemical composition, were studied over a wide temperature range by single‐crystal and powder X‐ray diffraction. Neither the interconversion between the two phases nor any polymorphic transitions were observed in the temperature range from 100 K to the melting points. This contrasts with the solvent‐mediated phase transition from the salt to the cocrystal in a slurry that has been documented earlier.