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Synthesis and crystal structure of an M 4 L 6 tetrahedral cage with outward‐facing pockets from a substituted pyrazolyl–pyridine ligand
Author(s) -
Al Rasbi Nawal K.,
Ward Michael D.
Publication year - 2018
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 17
ISSN - 2053-2296
DOI - 10.1107/s2053229618009683
Subject(s) - pyridine , chemistry , ligand (biochemistry) , denticity , crystal structure , perchlorate , ring (chemistry) , acetonitrile , crystallography , supramolecular chemistry , cobalt , stereochemistry , chelation , medicinal chemistry , inorganic chemistry , receptor , organic chemistry , ion , biochemistry
The self‐assembly of metal–polydentate ligands to give supramolecular tetrahedral complexes is of considerable current interest. A new ligand, 4‐benzyl‐2‐[1‐(2‐{[3‐(4‐benzylpyridin‐2‐yl)‐1 H ‐pyrazol‐1‐yl]methyl}benzyl)‐1 H ‐pyrazol‐3‐yl]pyridine ( L ), with chelating pyrazolyl–pyridine units substituted on the 4‐position of the pyridyl ring with benzyl units, has been synthesized and fully characterized. The self‐assembly of L with cobalt(II) gave rise to a tetrahedral cage (hexakis{μ‐4‐benzyl‐2‐[1‐(2‐{[3‐(4‐benzylpyridin‐2‐yl)‐1 H ‐pyrazol‐1‐yl]methyl}benzyl)‐1 H ‐pyrazol‐3‐yl]pyridine}perchloratotetracobalt(II) octakis(perchlorate) acetonitrile undecasolvate, [Co 4 (ClO 4 )(C 38 H 32 N 6 ) 6 ](ClO 4 ) 7 ·11CH 3 CN) with approximate T symmetry. The X‐ray crystal structure of the cage, i.e. [Co 4 L 6 ClO 4 ](ClO 4 ) 7 , shows that the substituted benzyl groups are oriented away from the centres of their respective ligands towards the Co II vertices, making small outward‐facing pockets from three benzyl rings at the corners of the tetrahedron.