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A fluorophore‐labelled copper complex: crystal structure, hybrid cyclic water–perchlorate cluster and biological properties
Author(s) -
Bhat Satish S.,
Revankar Vidyanand K.,
Shivalingegowda Naveen,
Lokanath N. K.
Publication year - 2017
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 17
ISSN - 2053-2296
DOI - 10.1107/s2053229617011639
Subject(s) - fluorophore , copper , cluster (spacecraft) , perchlorate , chemistry , crystal structure , materials science , crystallography , fluorescence , physics , computer science , optics , ion , organic chemistry , programming language
A fluorophore‐labelled copper(II) complex, aquabis(dimethylformamide‐κ O )(perchlorato‐κ O )[2‐(quinolin‐2‐yl)‐1,3‐oxazolo[4,5‐ f ][1,10]phenanthroline]copper(II) perchlorate monohydrate, [Cu(ClO 4 )(C 22 H 12 N 4 O)(C 3 H 7 NO) 2 (H 2 O)]ClO 4 ·H 2 O, has been synthesized and characterized. A cyclic hydrogen‐bonded water–perchlorate anionic cluster, i.e. [(ClO 4 ) 2 (H 2 O) 2 ] 2− , has been identified within the structure. Each cyclic anionic cluster unit is interconnected by hydrogen bonding to the cation. The cations join into an infinite hydrogen‐bonded chain running in the [010] direction. Furthermore, interaction of the complex with calf‐thymus DNA (CT‐DNA) and cellular localization within the cells was explored. Spectroscopic studies indicate that the compound has a good affinity for DNA and stains the nucleus of the cells.