Open AccessA microfluidic dosimetry cell to irradiate solutions with poorly penetrating radiations: a step towards online dosimetry for synchrotron beamlines
Author(s) -
Huart Lucie,
Nicolas Christophe,
Hervé du Penhoat Marie-Anne,
Guigner Jean-Michel,
Gosse Charlie,
Palaudoux Jérôme,
Lefrançois Stephane,
Mercere Pascal,
Dasilva Paulo,
Renault Jean-Philippe,
Chevallard Corinne
Publication year - 2021
Publication title -
journal of synchrotron radiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 99
ISSN - 1600-5775
DOI - 10.1107/s1600577521002691
Subject(s) - dosimetry , radiolysis , dosimeter , ionizing radiation , radiochemistry , synchrotron radiation , synchrotron , microfluidics , irradiation , linear energy transfer , materials science , aqueous solution , chemistry , nanotechnology , optics , nuclear medicine , nuclear physics , physics , medicine
Synchrotron radiation can induce sample damage, whether intended or not. In the case of sensitive samples, such as biological ones, modifications can be significant. To understand and predict the effects due to exposure, it is necessary to know the ionizing radiation dose deposited in the sample. In the case of aqueous samples, deleterious effects are mostly induced by the production of reactive oxygen species via water radiolysis. These species are therefore good indicators of the dose. Here the application of a microfluidic cell specifically optimized for low penetrating soft X‐ray radiation is reported. Sodium benzoate was used as a fluorescent dosimeter thanks to its specific detection of hydroxyl radicals, a radiolytic product of water. Measurements at 1.28 keV led to the determination of a hydroxyl production yield, G (HO . ), of 0.025 ± 0.004 µmol J −1 . This result is in agreement with the literature and confirms the high linear energy transfer behavior of soft X‐rays. An analysis of the important parameters of the microfluidic dosimetry cell, as well as their influences over dosimetry, is also reported.