Open AccessThe Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source
Author(s) -
Sierra Raymond G.,
Batyuk Alexander,
Sun Zhibin,
Aquila Andrew,
Hunter Mark S.,
Lane Thomas J.,
Liang Mengning,
Yoon Chun Hong,
Alonso-Mori Roberto,
Armenta Rebecca,
Castagna Jean-Charles,
Hollenbeck Michael,
Osier Ted O.,
Hayes Matt,
Aldrich Jeff,
Curtis Robin,
Koglin Jason E.,
Rendahl Theodore,
Rodriguez Evan,
Carbajo Sergio,
Guillet Serge,
Paul Rob,
Hart Philip,
Nakahara Kazutaka,
Carini Gabriella,
DeMirci Hasan,
Dao E. Han,
Hayes Brandon M.,
Rao Yashas P.,
Chollet Matthieu,
Feng Yiping,
Fuller Franklin D.,
Kupitz Christopher,
Sato Takahiro,
Seaberg Matthew H.,
Song Sanghoon,
van Driel Tim B.,
Yavas Hasan,
Zhu Diling,
Cohen Aina E.,
Wakatsuki Soichi,
Boutet Sébastien
Publication year - 2019
Publication title -
journal of synchrotron radiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 99
ISSN - 1600-5775
DOI - 10.1107/s1600577519001577
Subject(s) - femtosecond , linear particle accelerator , laser , optics , ultrashort pulse , multiplexing , free electron laser , materials science , physics , computer science , beam (structure) , telecommunications
The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world's first hard X‐ray free‐electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X‐rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological measurements. It is also capable of performing various time‐resolved measurements. The MFX design consists of a versatile base system capable of supporting multiple methods, techniques and experimental endstations. The primary techniques supported are forward scattering and crystallography, with capabilities for various spectroscopic methods and time‐resolved measurements. The location of the MFX instrument allows for utilization of multiplexing methods, increasing user access to LCLS by running multiple experiments simultaneously.