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Monochromatic computed microtomography using laboratory and synchrotron sources and X‐ray fluorescence analysis for comprehensive analysis of structural changes in bones
Author(s) -
Buzmakov Alexey,
Chukalina Marina,
Nikolaev Dmitry,
Gulimova Victoriya,
Saveliev Sergey,
Tereschenko Elena,
Seregin Alexey,
Senin Roman,
Zolotov Denis,
Prun Victor,
Shaefer Gerald,
Asadchikov Victor
Publication year - 2015
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s1600576715006214
Subject(s) - anatomy , synchrotron , skeleton (computer programming) , materials science , ischium , biomedical engineering , biology , physics , medicine , optics , pelvis
A combination of X‐ray tomography at different wavelengths and X‐ray fluorescence analysis was applied in the study of two types of bone tissue changes: prolonged presence in microgravity conditions and age‐related bone growth. The proximal tail vertebrae of geckos were selected for investigation because they do not bear the supporting load in locomotion, which allows them to be considered as an independent indicator of gravitational influence. For the vertebrae of geckos no significant differences were revealed in the elemental composition of the flight samples and the synchronous control samples. In addition, the gecko bone tissue samples from the jaw apparatus, spine and shoulder girdle were measured. The dynamics of structural changes in the bone tissue growth was studied using samples of a human fetal hand. The hands of human fetuses of 11–15 weeks were studied. Autonomous zones of calcium accumulation were found not only in individual fingers but in each of the investigated phalanges. The results obtained are discussed.