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The Bio‐SANS instrument at the High Flux Isotope Reactor of Oak Ridge National Laboratory
Author(s) -
Heller William T.,
Urban Volker S.,
Lynn Gary W.,
Weiss Kevin L.,
O'Neill Hugh M.,
Pingali Sai Venkatesh,
Qian Shuo,
Littrell Kenneth C.,
Melnichenko Yuri B.,
Buchanan Michelle V.,
Selby Douglas L.,
Wignall George D.,
Butler Paul D.,
Myles Dean A.
Publication year - 2014
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s1600576714011285
Subject(s) - oak ridge national laboratory , neutron scattering , national laboratory , sample (material) , flux (metallurgy) , ridge , nuclear engineering , neutron , nuclear physics , environmental science , materials science , physics , engineering , engineering physics , geology , paleontology , metallurgy , thermodynamics
Small‐angle neutron scattering (SANS) is a powerful tool for characterizing complex disordered materials, including biological materials. The Bio‐SANS instrument of the High Flux Isotope Reactor of Oak Ridge National Laboratory (ORNL) is a high‐flux low‐background SANS instrument that is, uniquely among SANS instruments, dedicated to serving the needs of the structural biology and biomaterials communities as an open‐access user facility. Here, the technical specifications and performance of the Bio‐SANS are presented. Sample environments developed to address the needs of the user program of the instrument are also presented. Further, the isotopic labeling and sample preparation capabilities available in the Bio‐Deuteration Laboratory for users of the Bio‐SANS and other neutron scattering instruments at ORNL are described. Finally, a brief survey of research performed using the Bio‐SANS is presented, which demonstrates the breadth of the research that the instrument's user community engages in.