Open AccessA new on‐axis multimode spectrometer for the macromolecular crystallography beamlines of the Swiss Light Source
Author(s) -
Owen Robin L.,
Pearson Arwen R.,
Meents Alke,
Boehler Pirmin,
Thominet Vincent,
SchulzeBriese Clemens
Publication year - 2009
Publication title -
journal of synchrotron radiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 99
ISSN - 1600-5775
DOI - 10.1107/s0909049508040120
Subject(s) - beamline , spectrometer , synchrotron , raman spectroscopy , optics , synchrotron radiation , light source , absorption (acoustics) , multi mode optical fiber , laser , materials science , physics , optical fiber , beam (structure)
X‐ray crystallography at third‐generation synchrotron sources permits tremendous insight into the three‐dimensional structure of macromolecules. Additional information is, however, often required to aid the transition from structure to function. In situ spectroscopic methods such as UV–Vis absorption and (resonance) Raman can provide this, and can also provide a means of detecting X‐ray‐induced changes. Here, preliminary results are introduced from an on‐axis UV–Vis absorption and Raman multimode spectrometer currently being integrated into the beamline environment at X10SA of the Swiss Light Source. The continuing development of the spectrometer is also outlined.